Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.87 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335749 | 0.93 | ASAH1 (1.00) | ASAH1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL17343770 | 0.88 | ASAH1 (0.89) | ASAH1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9848444 | 0.84 | ASAH1 (0.69) | ASAH1CERT1ALDH1A1ACER2EPHX2 | |
| SCHEMBL9848372 | 0.84 | ASAH1 (0.69) | ASAH1CERT1ALDH1A1ACER2EPHX2 | |
| SCHEMBL12435702 | 0.84 | ASAH1 (0.81) | ASAH1ALDH1A1EPHX2FAAH | |
| SCHEMBL12672800 | 0.81 | ASAH1 (0.76) | ASAH1NPC1RAB9ASMN1; SMN2BCAT2 | |
| SCHEMBL18741947 | 0.81 | ASAH1 (0.76) | ASAH1CERT1ALDH1A1ACER2EPHX2 | |
| SCHEMBL21634180 | 0.80 | ASAH1 (0.75) | ASAH1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL1233061 | 0.80 | ASAH1 (0.75) | ASAH1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6646425 | 0.76 | ASAH1 (0.68) | ASAH1SMN1; SMN2ALDH1A1ACER2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799033-A1 | USE OF MONO AND BICARBOXYLIC ACID AMIDES FOR THE MANUFACTURE OF A MEDICAMENT ACTIVE AT THE PERIPHERAL CANNABINOID RECEPTOR | LIFEGROUP S.p.A. (IT) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996018391-A2 | USE OF MONO AND BICARBOXYLIC ACID AMIDES FOR THE MANUFACTURE OF A MEDICAMENT ACTIVE AT THE PERIPHERAL CANNABINOID RECEPTOR | LIFEGROUP S.P.A. (IT) | 1996-06-20 | — | — | WO | disclosed |