Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.53 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848444 | 1.00 | ASAH1 (0.69) | ASAH1EPHX2ALDH1A1ACER2CERT1 | |
| SCHEMBL8776663 | 0.84 | ASAH1 (0.87) | ASAH1EPHX2ALDH1A1ACER2CERT1 | |
| SCHEMBL18741947 | 0.83 | ASAH1 (0.76) | ASAH1EPHX2ALDH1A1ACER2CERT1 | |
| SCHEMBL8335749 | 0.82 | ASAH1 (1.00) | ASAH1EPHX2ALDH1A1ACER2CERT1 | |
| SCHEMBL6646425 | 0.78 | ASAH1 (0.68) | ASAH1EPHX2ALDH1A1ACER2MEN1 | |
| SCHEMBL9716121 | 0.78 | ASAH1 (0.63) | ASAH1ALDH1A1ACER2CERT1 | |
| SCHEMBL9848504 | 0.78 | ASAH1 (0.63) | ASAH1ALDH1A1ACER2CERT1 | |
| SCHEMBL18768732 | 0.77 | MMP2 (0.72) | ASAH1EPHX2MMP2MEN1KMT2A | |
| SCHEMBL9848496 | 0.77 | ASAH1 (0.67) | ASAH1EPHX2ALDH1A1ACER2CERT1 | |
| SCHEMBL9848510 | 0.77 | ASAH1 (0.67) | ASAH1EPHX2ALDH1A1ACER2CERT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |