Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | CCR2 | P41597 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776646 | 0.89 | GAA (0.54) | POLBNAMPTCCR2KCNH2CYP2D6 | |
| SCHEMBL8776666 | 0.88 | POLB (0.67) | POLBNAMPTCCR2CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL9057311 | 0.84 | POLB (0.51) | POLBNAMPTCCR2KCNH2CYP2D6 | |
| SCHEMBL27498807 | 0.82 | GAA (0.51) | POLBNAMPTCCR2KCNH2CYP2D6 | |
| SCHEMBL9058915 | 0.81 | MAPT (0.46) | POLBCCR2MAPTFAAH | |
| Hydrochloric Acid SCHEMBL9059017 | 0.80 | MAPT (0.45) | POLBNAMPTCCR2CYP2D6CYP3A4 | |
| SCHEMBL8483552 | 0.79 | POLB (0.45) | POLBNAMPTKCNH2CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL9057956 | 0.78 | POLB (0.45) | POLBNAMPTCCR2CYP2C19MAPT | |
| Hydrochloric Acid SCHEMBL9058920 | 0.77 | POLB (0.44) | POLBNAMPTCCR2KCNH2CYP2D6 | |
| SCHEMBL1942072 | 0.75 | CYP3A4 (0.64) | CCR2KCNH2CYP2D6CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799202-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1997-10-08 | — | — | EP | disclosed |