Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632822 | 0.78 | HRH3 (0.48) | MAPTLMNAUSP2CYP3A4RECQL | |
| SCHEMBL7066229 | 0.78 | HRH3 (0.48) | MAPTLMNAUSP2CYP3A4RECQL | |
| SCHEMBL4105971 | 0.76 | SMPD1 (0.43) | MAPT | |
| SCHEMBL1499940 | 0.76 | SMPD1 (0.43) | MAPT | |
| SCHEMBL1064519 | 0.76 | SMPD1 (0.43) | MAPT | |
| SCHEMBL2306623 | 0.73 | FDPS (0.41) | MAPT | |
| SCHEMBL31153231 | 0.70 | TSHR (0.42) | MAPTABCC4ALDH1A1LMNALPAR3 | |
| SCHEMBL31153236 | 0.70 | TSHR (0.42) | MAPTABCC4ALDH1A1LMNALPAR3 | |
| SCHEMBL6900617 | 0.70 | TSHR (0.42) | MAPTABCC4ALDH1A1LMNALPAR3 | |
| SCHEMBL9245891 | 0.70 | TSHR (0.42) | MAPTABCC4ALDH1A1LMNALPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475130-B1 | Siloxane derivative, its use as emulsifier and cosmetic preparations | KAO CORP (JP) | 1997-12-03 | — | — | EP | disclosed |
| US-5466849-A | Cosmetics | KAO CORPORATION (JP) | 1995-11-14 | — | — | US | disclosed |
| US-5306838-A | Cosmetics, storage stability | KAO CORPORATION (JP) | 1994-04-26 | — | — | US | disclosed |
| US-5144054-A | Reaction Products with Alkenyl Glyceryl Ether | KAO CORPORATION (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0475130-A2 | Siloxane derivatives, producing method thereof and agents including siloxane derivative | KAO CORPORATION (JP) | 1992-03-18 | — | — | EP | disclosed |