Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18780250 | 0.88 | NPC1 (0.52) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL13304204 | 0.87 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL15380 | 0.84 | NPC1 (0.48) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL29362516 | 0.84 | NPC1 (0.48) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL12387038 | 0.83 | NPC1 (0.59) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL714505 | 0.83 | NPC1 (0.46) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL276066 | 0.82 | NPC1 (0.46) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL21169728 | 0.79 | NPC1 (0.43) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL10061927 | 0.79 | NPC1 (0.64) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL10194930 | 0.79 | NPC1 (0.54) | NPC1RAB9APOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711778-B1 | Sunscreens, sunscreen compositions and use thereof | OREAL (FR) | 1997-12-10 | — | — | EP | disclosed |
| US-5569451-A | SUNSCREEN AGENT | L'OREAL (FR) | 1996-10-29 | — | — | US | disclosed |
| EP-0711778-A1 | Sunscreens, sunscreen compositions and use thereof | L'OREAL (FR) | 1996-05-15 | — | — | EP | disclosed |