SCHEMBL8777073

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8777284	0.88	PDE10A (0.46)	MAPTTP53KDM4ENPC1LMNA
	SCHEMBL8777251	0.87	PDE10A (0.48)	MAPTALDH1A1KDM4ESMN1; SMN2RAB9A
	SCHEMBL8776948	0.83	NPC1 (0.51)	MAPTALDH1A1KDM4ESMN1; SMN2NPC1
	SCHEMBL8777277	0.83	SLC6A3 (0.43)	ALDH1A1KDM4EHPGDLMNAPKM
	SCHEMBL8777041	0.83	KMT2A (0.48)	MAPTTP53ALDH1A1KDM4EHPGD
	SCHEMBL8777229	0.83	CYP1A2 (0.48)	MAPTALDH1A1KDM4ENPC1RAB9A
	SCHEMBL8777140	0.83	CYP1A2 (0.50)	MAPTALDH1A1KDM4ESMN1; SMN2NPC1
	SCHEMBL8776881	0.83	CYP1A2 (0.50)	MAPTTP53ALDH1A1KDM4EHPGD
	SCHEMBL28574625	0.83	CYP1A2 (0.56)	MAPTTP53ALDH1A1KDM4EHPGD
	SCHEMBL8776938	0.83	PDE10A (0.51)	MAPTALDH1A1KDM4ESMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.