Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777383 | 1.00 | LMNA (0.52) | LMNACES2CES1MAPK1MEN1 | |
| SCHEMBL257213 | 1.00 | LMNA (0.52) | LMNACES2CES1MAPK1MEN1 | |
| SCHEMBL8777365 | 1.00 | LMNA (0.52) | LMNACES2CES1MAPK1MEN1 | |
| SCHEMBL1148745 | 1.00 | LMNA (0.52) | LMNACES2CES1MAPK1MEN1 | |
| SCHEMBL8777385 | 1.00 | LMNA (0.52) | LMNACES2CES1MAPK1MEN1 | |
| SCHEMBL851397 | 1.00 | LMNA (0.52) | LMNACES2CES1MAPK1MEN1 | |
| SCHEMBL2545365 | 0.98 | LMNA (0.50) | LMNACES2CES1MAPK1MEN1 | |
| SCHEMBL11029163 | 0.98 | LMNA (0.50) | LMNACES2CES1MAPK1MEN1 | |
| SCHEMBL21065464 | 0.98 | LMNA (0.50) | LMNACES2CES1MAPK1MEN1 | |
| SCHEMBL17818487 | 0.98 | LMNA (0.50) | LMNACES2CES1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471498-B1 | Optical resolution method | KANKYO KAGAKU CENTER (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5510520-A | Optical resolution method | KANKYO KAGAKU CENTER CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| US-5395962-A | Optical resolution method | KANKYO KAGAKU CENTER CO., LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0471498-A2 | Optical resolution method | KANKYO KAGAKU CENTER CO., LTD (JP) | 1992-02-19 | — | — | EP | disclosed |