Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL8777375

CC1CO1.OCCOCCO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
MAPK1 P28482 1/20 0.53
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 2/20 0.43
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.32
CHRM2 P08172 2/20 0.31
CHRM5 P08912 2/20 0.31
CHRM3 P20309 2/20 0.31
CHRM4 P08173 1/20 0.31
PDK1 Q15118 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraethylene Glycol SCHEMBL8003700 0.97 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
Tetraethylene Glycol SCHEMBL9862346 0.87 MEN1 (0.44) TSHRMAPK1MEN1KMT2AALDH1A1
Butoxyethanol SCHEMBL28548494 0.87 TSHR (0.68) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL9862341 0.87 MEN1 (0.44) TSHRMAPK1MEN1KMT2AALDH1A1
2-Methoxyethanol SCHEMBL11702930 0.82
Propylene Oxide SCHEMBL9874479 0.80 CHRM2 (0.37) TSHRCHRM2CHRM5CHRM3CHRM4
Propylene Oxide SCHEMBL168597 0.80
Propylene Oxide SCHEMBL9873297 0.80 CHRM2 (0.37) TSHRCHRM2CHRM5CHRM3CHRM4
Propylene Oxide SCHEMBL7556563 0.80 CHRM2 (0.37) TSHRCHRM2CHRM5CHRM3CHRM4
Propylene Oxide SCHEMBL28924060 0.80 USP2 (0.46) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7233316-A None JP disclosed
EP-3818097-A1 ADHESIVE METHOD USING TWO-COMPONENT ADHESIVES BASED ON COMPOUNDS HAVING CYCLOTHIOCARBONATE UNITS BASF SE (DE) 2021-05-12 EP disclosed
WO-2020007634-A1 ADHESIVE METHOD USING TWO-COMPONENT ADHESIVES BASED ON COMPOUNDS HAVING CYCLOTHIOCARBONATE UNITS BASF SE (DE) 2020-01-09 WO disclosed
EP-0397036-B1 Process for producing polyalkylene oxide derivatives ASAHI GLASS CO LTD (JP) 1997-12-17 EP disclosed
JP-H07233316-A CURABLE COMPOSITION ASAHI GLASS CO LTD 1995-09-05 JP disclosed
US-5223583-A PROCESS FOR PRODUCING POLYALKYLENE OXIDE DERIVATIVES ASAHI GLASS COMPANY LTD. (JP) 1993-06-29 US disclosed
EP-0397036-A2 Process for producing polyalkylene oxide derivatives ASAHI GLASS COMPANY LTD. (JP) 1990-11-14 EP disclosed
US-4701476-A Polyurethane elastomers prepared from high molecular weight prepolymers THE DOW CHEMICAL COMPANY (US) 1987-10-20 US disclosed