SCHEMBL87774

SCHEMBL87774

O=c1c(Cl)c(-c2ccccc2)oc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 2/20 1.00
KMT2A Q03164 5/20 0.65
MEN1 O00255 4/20 0.65
KDM4E B2RXH2 3/20 0.65
CYP3A4 P08684 3/20 0.65
LMNA P02545 3/20 0.65
ALOX15 P16050 2/20 0.65
MAPK1 P28482 2/20 0.65
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
TP53 P04637 2/20 0.65
DDR2 Q16832 1/20 0.65
CA12 O43570 1/20 0.65
ABCB1 P08183 1/20 0.65
CALM1 P0DP23 1/20 0.65
AR P10275 1/20 0.65
PKM P14618 1/20 0.65
CYP1B1 Q16678 1/20 0.65
CA9 Q16790 1/20 0.65
ABCG2 Q9UNQ0 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31584712 1.00 ADORA3 (1.00) ADORA3KMT2AMEN1KDM4ECYP3A4
SCHEMBL12825536 0.87 ADORA3 (0.77) ADORA3KMT2AMEN1KDM4ECYP3A4
SCHEMBL27906926 0.85 ADORA3 (0.73) ADORA3KMT2AMEN1KDM4ECYP3A4
SCHEMBL31060980 0.83 ADORA3 (1.00) ADORA3KMT2AMEN1KDM4ECYP3A4
SCHEMBL30741235 0.83 ADORA3 (1.00) ADORA3KMT2AMEN1KDM4ECYP3A4
SCHEMBL12941180 0.83 ABCG2 (0.74) ADORA3KMT2AMEN1KDM4ECYP3A4
SCHEMBL1458117 0.82 ADORA3 (0.68) ADORA3KMT2AMEN1KDM4ECYP3A4
SCHEMBL693914 0.81 KMT2A (0.69) ADORA3KMT2AMEN1KDM4ECYP3A4
SCHEMBL29349443 0.81 KMT2A (0.69) ADORA3KMT2AMEN1KDM4ECYP3A4
SCHEMBL27940008 0.81 KDM4E (0.74) ADORA3KMT2AMEN1KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 376 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119454719-A Application of tripterine as guiding inhibitor of mycobacterium tuberculosis acetyl hydroxy acid synthase 重庆医科大学国际体外诊断研究院 2025-02-18 CN disclosed
CN-118873822-A Treatment of gastrointestinal disorders with TNF inhibitors 比奥拉治疗股份有限公司 2024-11-01 CN disclosed
US-20240224409-A1 ELECTRONIC DEVICE AND MANUFACTURING METHOD THEREOF FUJIFILM CORPORATION (JP) 2024-07-04 US disclosed
US-20240206077-A1 MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2024-06-20 US disclosed
US-20240196519-A1 ELECTRONIC DEVICE AND MANUFACTURING METHOD THEREOF FUJIFILM CORPORATION (JP) 2024-06-13 US disclosed
US-20240186261-A1 ELECTRONIC DEVICE AND MANUFACTURING METHOD THEREOF FUJIFILM CORPORATION (JP) 2024-06-06 US disclosed
US-20240147630-A1 ELECTRONIC DEVICE AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2024-05-02 US disclosed
WO-2024082757-A1 FLAVONOID COMPOUNDS, GENES ASSOCIATED WITH BIOSYNTHESIS THEREOF AND USE THEREOF 中国科学院青岛生物能源与过程研究所 2024-04-25 WO disclosed
CN-117917472-A Aspergillus candidus strain for high-yield of chloroflavus bacteria and application thereof 中国科学院青岛生物能源与过程研究所 2024-04-23 CN disclosed
CN-117590691-A Photosensitive resin composition 中央硝子株式会社 2024-02-23 CN disclosed
EP-1389521-A2 Thermosensitive/photosensitive resin composition Fuji Photo Film Co., Ltd. (JP) 2004-02-18 EP disclosed
US-20030190554-A1 Photopolymerization; development using alkalinity developer FUJIFILM CORPORATION (JP) 2003-10-09 US disclosed
US-20030091933-A1 Photosensitive composition and negative working lithographic printing plate FUJIFILM CORPORATION (JP) 2003-05-15 US disclosed
EP-1288720-A1 Plate-making method of printing plate FUJI PHOTO FILM CO., LTD. (JP) 2003-03-05 EP disclosed
EP-1249731-A2 Photosensitive composition and negative working lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2002-10-16 EP disclosed
EP-0860741-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 2001-05-16 EP disclosed
US-6051367-A COMPRISING ONE OR MORE ADDITION-POLYMERIZABLE ETHYLENICALLY UNSATURATED COMPOUNDS AND A SPECIFIC OXIME ETHER COMPOUND; HIGH SENSITIVE TO ACTINIC RAYS RANGING FROM ULTRAVIOLET TO VISIBLE LIGHT, IMPROVED FILM STRENGTH FUJI PHOTO FILM CO., LTD. (JP) 2000-04-18 US disclosed
EP-0973516-A1 USE OF HALO AND/OR NITRO-SUBSTITUTED FLAVONOIDS AS ANXYOLITICS University of Strathclyde (GB) 2000-01-26 EP disclosed
WO-1998044920-A1 USE OF HALO AND/OR NITRO-SUBSTITUTED FLAVONOIDS AS ANXYOLITICS UNIVERSITY OF STRATHCLYDE (GB) 1998-10-15 WO disclosed
EP-0860741-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1998-08-26 EP disclosed