SCHEMBL8777582

SCHEMBL8777582

CCCCCCCCn1c(C)c(C2(c3ccc(N(C)C)cc3OC)OC(=O)c3cccnc32)c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 13/20 0.39
CNR1 P21554 3/20 0.38
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TLR8 Q9NR97 1/20 0.34
SLC6A3 Q01959 1/20 0.34
PSEN1 P49768 1/20 0.34
PSEN2 P49810 1/20 0.34
APH1B Q8WW43 1/20 0.34
NCSTN Q92542 1/20 0.34
APH1A Q96BI3 1/20 0.34
PSENEN Q9NZ42 1/20 0.34
PLA2G2A P14555 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1767186 0.95 CNR2 (0.40) CNR2CNR1MEN1KMT2ASLC6A3
SCHEMBL1767232 0.93 CNR2 (0.38) CNR2CNR1MEN1KMT2ATLR8
SCHEMBL1766873 0.93 CNR2 (0.38) CNR2CNR1MEN1KMT2ATLR8
SCHEMBL1767278 0.93 CNR2 (0.38) CNR2CNR1MEN1KMT2ATLR8
SCHEMBL8777592 0.89 PLA2G2A (0.33) MEN1KMT2APSEN1PSEN2APH1B
SCHEMBL10662884 0.89 TDP1 (0.33) MEN1KMT2APLA2G2A
SCHEMBL29460368 0.88 CNR2 (0.39) CNR2CNR1MEN1KMT2ASLC6A3
SCHEMBL29598989 0.88 CNR2 (0.39) CNR2CNR1MEN1KMT2ASLC6A3
SCHEMBL51632 0.88 CNR2 (0.39) CNR2CNR1MEN1KMT2ASLC6A3
SCHEMBL6865145 0.88 CNR2 (0.39) CNR2CNR1MEN1KMT2ASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed