SCHEMBL8777680

SCHEMBL8777680

CCCCCN(CCCCC)c1ccc(C(OC)c2ccc(N(C)C)cc2)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.36
MAPT P10636 2/20 0.34
PKM P14618 1/20 0.34
HTT P42858 1/20 0.34
MCL1 Q07820 1/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
SLC16A3 O15427 1/20 0.34
SLC16A1 P53985 1/20 0.34
CNR2 P34972 2/20 0.33
SLC2A1 P11166 1/20 0.33
CRHR1 P34998 3/20 0.32
TDP1 Q9NUW8 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777739 0.96 GAA (0.36) GAAMAPTPKMHTTMCL1
SCHEMBL8777681 0.88 GAA (0.37) GAAMAPTPKMHTTMCL1
SCHEMBL8777779 0.86 S100B (0.39) GAAMAPTPKMHTTMCL1
SCHEMBL8777614 0.86 S100B (0.43) GAAMAPTPKMHTTMCL1
SCHEMBL8777568 0.86 SLC16A3 (0.37) GAAMAPTMEN1KMT2ASLC16A3
SCHEMBL8777540 0.85 GAA (0.36) GAAMAPTPKMHTTMCL1
SCHEMBL8777651 0.84 CYP2D6 (0.40) GAAMAPTPKMHTTMCL1
SCHEMBL8777687 0.84 GAA (0.35) GAAMAPTPKMHTTMCL1
SCHEMBL8777735 0.83 SLC16A3 (0.41) GAAMAPTMEN1KMT2ASLC16A3
SCHEMBL8777640 0.83 SLC2A1 (0.42) GAAMAPTSLC2A1CRHR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed