SCHEMBL8777734

SCHEMBL8777734

CCCCNS(=O)(=O)c1ccc(OC)c(N)c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.71
LMNA P02545 1/20 0.71
HTT P42858 1/20 0.71
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
MMP1 P03956 1/20 0.62
MMP2 P08253 1/20 0.62
MMP9 P14780 1/20 0.62
MMP8 P22894 1/20 0.62
MMP13 P45452 1/20 0.62
F2 P00734 3/20 0.56
PRSS1 P07477 3/20 0.56
PRSS2 P07478 3/20 0.56
PRSS3 P35030 3/20 0.56
ALDH1A1 P00352 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C19 P33261 1/20 0.56
POLB P06746 1/20 0.54
KMT2A Q03164 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11573896 0.94 MAPK1 (0.80) MAPK1LMNAHTTCA1CA2
SCHEMBL2955220 0.94 MAPK1 (0.80) MAPK1LMNAHTTCA1CA2
SCHEMBL11311669 0.90 LMNA (0.59) MAPK1LMNAHTTCA1CA2
SCHEMBL9858703 0.88 HTT (0.89) MAPK1LMNAHTTALDH1A1CYP1A2
SCHEMBL11573058 0.87 CA1 (0.61) MAPK1LMNAHTTCA1CA2
SCHEMBL16134622 0.85 CA12 (0.54) MAPK1LMNAHTTCA1CA2
SCHEMBL2791351 0.83 HTT (1.00) MAPK1LMNAHTTALDH1A1POLB
SCHEMBL2791185 0.83 HTT (1.00) MAPK1LMNAHTTALDH1A1POLB
SCHEMBL11513902 0.80 MAPK1 (0.78) MAPK1LMNAHTTALDH1A1CYP1A2
SCHEMBL11574192 0.79 CA1 (0.54) MAPK1LMNAHTTCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9759733-B1 Mass produced, low cost, portable test kit for the detection and identification of narcotics VERITEQUE USA, INC. 2017-09-12 US claimed
US-9759733-B1 Mass produced, low cost, portable test kit for the detection and identification of narcotics VERITEQUE USA, INC. 2017-09-12 US disclosed
EP-0585873-B1 Method of preparing disazo pigments CLARIANT GMBH (DE) 1997-12-29 EP disclosed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed
EP-0518909-B1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AG (DE) 1994-05-25 EP disclosed
EP-0585873-A1 Method of preparing disazo pigments HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-09 EP disclosed
EP-0518909-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE. HOECHST AG (DE) 1992-12-23 EP disclosed
EP-0316649-B1 WATER INSOLUBLE AZO COLOURING AGENTS, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-22 EP disclosed
WO-1991013941-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-19 WO disclosed
US-4165967-A HYDROXY-PYRIDINE OR PYRIDONE COUPLERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1979-08-28 US disclosed
US-4162893-A Process for dyeing human hair with diazo salts HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1979-07-31 US disclosed
US-4125368-A Metallized monoazo dyes TOMS RIVER CHEMICAL CORP. (US) 1978-11-14 US disclosed
US-4094637-A Process for the printing with developing dyes HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed
US-4065254-A DIAZO DYES, LEATHER, COTTON, WOOL CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4058515-A Metallized phenyl-azo-naphthol compounds TOMS RIVER CHEMICAL CORPORATION (US) 1977-11-15 US disclosed
US-3974534-A Process for vacuum treatment of textile materials BURLINGTON INDUSTRIES, INC. (US) 1976-08-17 US disclosed
US-3961887-A Process for the printing of cellulose containing textile material HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed
US-3961884-A Process for dyeing textile material of polyester fiber/cellulose blends HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed
US-3930840-A RIPENING OF SUGARCANE BY USE OF CERTAIN ALCOHOLIC AND ETHOXYLATED COMPOUNDS HAWAIIAN SUGAR PLANTERS' ASSOCIATION (US) 1976-01-06 US disclosed