SCHEMBL8777744

SCHEMBL8777744

CSc1ccc2c(c1)C(=O)c1cccc(N)c1C2=O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.64
PTPRC P08575 2/20 0.50
MAOA P21397 2/20 0.47
MAOB P27338 1/20 0.47
CSNK1A1 P48729 2/20 0.46
CSNK1D P48730 2/20 0.46
CSNK1G1 Q9HCP0 2/20 0.46
FGR P09769 1/20 0.46
PIM1 P11309 1/20 0.46
DYRK1A Q13627 1/20 0.46
HIPK2 Q9H2X6 1/20 0.46
ALDH1A1 P00352 8/20 0.45
MAPK1 P28482 7/20 0.45
SMN1; SMN2 Q16637 6/20 0.45
RAB9A P51151 5/20 0.45
L3MBTL1 Q9Y468 5/20 0.45
NPC1 O15118 3/20 0.45
CYP3A4 P08684 2/20 0.45
TSHR P16473 2/20 0.45
CASP3 P42574 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11294862 0.83 ELANE (0.55) PTPRCMAOAALDH1A1MAPK1SMN1; SMN2
SCHEMBL9846493 0.82 ADORA2A (0.65) ADORA2APTPRCMAOAMAOBCSNK1A1
SCHEMBL9846537 0.82 ADORA2A (0.65) ADORA2APTPRCMAOAMAOBCSNK1A1
SCHEMBL9811057 0.81 ELANE (0.53) PTPRCMAOAALDH1A1MAPK1SMN1; SMN2
SCHEMBL30610034 0.81 ADORA2A (0.68) ADORA2APTPRCMAOAMAOBCSNK1A1
SCHEMBL14174532 0.81 ADORA2A (0.68) ADORA2APTPRCMAOAMAOBCSNK1A1
SCHEMBL4444783 0.80 ADORA2A (0.72) ADORA2APTPRCMAOAMAOBCSNK1A1
SCHEMBL30377911 0.80 ADORA2A (0.72) ADORA2APTPRCMAOAMAOBCSNK1A1
SCHEMBL29361856 0.80 ADORA2A (0.72) ADORA2APTPRCMAOAMAOBCSNK1A1
SCHEMBL8773084 0.80 ADORA2A (0.72) ADORA2APTPRCMAOAMAOBCSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
EP-0585873-B1 Method of preparing disazo pigments CLARIANT GMBH (DE) 1997-12-29 EP disclosed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed
EP-0518909-B1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AG (DE) 1994-05-25 EP disclosed
EP-0585873-A1 Method of preparing disazo pigments HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-09 EP disclosed
EP-0518909-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE. HOECHST AG (DE) 1992-12-23 EP disclosed
EP-0316649-B1 WATER INSOLUBLE AZO COLOURING AGENTS, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-22 EP disclosed
WO-1991013941-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-19 WO disclosed
US-5026831-A Water-insoluble disazo colorants having hetero-bicyclic methylene-active compounds as coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed
US-4284411-A CONDENSATION, PIGMENTING BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed
US-4260540-A SPIN DYEING POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
EP-0023617-A1 Anthraquinone-azo compounds, process for their preparation and their use as pigments BAYER AG (DE) 1981-02-11 EP disclosed
EP-0023648-A1 Anthraquinone-azomethine compounds, process for their preparation; process for dyeing synthetic fibre materials as well as for pigmenting organic macromolecular materials BAYER AG (DE) 1981-02-11 EP disclosed
US-4246401-A Axomethine pigments BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
EP-0020077-A1 Quaternary pyrazole derivatives, process for their preparation and their use as fungicides and bactericides CILAG-CHEMIE A.G. (CH) 1980-12-10 EP disclosed
EP-0018538-A2 Anthraquinone derivatives, process for their preparation, process for the pigmentation of organic macromolecular materials and pigmented organic macromolecular material BAYER AG (DE) 1980-11-12 EP disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
EP-0008627-A2 Quinazoline derivatives, azo dyes derived from the quinazolines and their use as pigments BAYER AG (DE) 1980-03-19 EP disclosed
EP-0008063-A1 Azomethine derivatives of anthraquinones, methods for their preparation, their use in the pigmentation of organic macromolecular compounds and the materials thus obtained BAYER AG (DE) 1980-02-20 EP disclosed