SCHEMBL8773084

SCHEMBL8773084

Nc1ccc2c(c1)C(=O)c1c(N)cccc1C2=O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.72
ALDH1A1 P00352 8/20 0.69
SMN1; SMN2 Q16637 5/20 0.69
MAPK1 P28482 5/20 0.69
NPC1 O15118 4/20 0.69
RAB9A P51151 4/20 0.69
TDP1 Q9NUW8 4/20 0.69
CYP3A4 P08684 3/20 0.69
TSHR P16473 2/20 0.69
TP53 P04637 1/20 0.69
MEN1 O00255 7/20 0.61
KMT2A Q03164 7/20 0.61
POLB P06746 6/20 0.61
PTPRC P08575 3/20 0.61
LMNA P02545 3/20 0.61
HPGD P15428 3/20 0.61
BLM P54132 3/20 0.61
NPSR1 Q6W5P4 2/20 0.61
HTT P42858 2/20 0.61
ALOX12 P18054 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4444783 1.00 ADORA2A (0.72) ADORA2AALDH1A1SMN1; SMN2MAPK1NPC1
SCHEMBL30377911 1.00 ADORA2A (0.72) ADORA2AALDH1A1SMN1; SMN2MAPK1NPC1
SCHEMBL29361856 1.00 ADORA2A (0.72) ADORA2AALDH1A1SMN1; SMN2MAPK1NPC1
SCHEMBL7225540 0.91 ALDH1A1 (0.66) ADORA2AALDH1A1SMN1; SMN2MAPK1NPC1
Hydrochloric Acid SCHEMBL27414025 0.89 ALDH1A1 (0.63) ADORA2AALDH1A1SMN1; SMN2MAPK1NPC1
SCHEMBL28314104 0.88 MAOA (0.67) ADORA2AALDH1A1SMN1; SMN2MAPK1NPC1
SCHEMBL28314083 0.88 MAOA (0.67) ADORA2AALDH1A1SMN1; SMN2MAPK1NPC1
SCHEMBL6945771 0.87 PTPRC (0.69) ADORA2AALDH1A1SMN1; SMN2MAPK1NPC1
SCHEMBL1557667 0.85 ADORA2A (1.00) ADORA2AALDH1A1SMN1; SMN2MAPK1NPC1
SCHEMBL29701006 0.85 ADORA2A (1.00) ADORA2AALDH1A1SMN1; SMN2MAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102020865-B Method for manufacturing grey dye by utilizing 1-amino anthraquinone production waste residues JIANGSU YABANG DYE CO LTD 2013-04-10 CN claimed
CN-102020864-B Method for manufacturing yellow dye by utilizing 1-amino anthraquinone production waste residues JIANGSU YABANG DYE CO LTD 2013-04-10 CN claimed
CN-102020865-A Method for manufacturing grey dye by utilizing 1-amino anthraquinone production waste residues JIANGSU YABANG DYE CO LTD 2011-04-20 CN claimed
CN-102020864-A Method for manufacturing yellow dye by utilizing 1-amino anthraquinone production waste residues JIANGSU YABANG DYE CO LTD 2011-04-20 CN claimed
CN-113304763-B Catalyst for preparing amino anthraquinone by hydrogenation, preparation method and application thereof 青岛福凯橡塑新材料有限公司 2023-04-25 CN disclosed
CN-113304763-A Catalyst for preparing aminoanthraquinone through hydrogenation, preparation method and application thereof 青岛福凯橡塑新材料有限公司 2021-08-27 CN disclosed
CN-102020864-B Method for manufacturing yellow dye by utilizing 1-amino anthraquinone production waste residues JIANGSU YABANG DYE CO LTD 2013-04-10 CN disclosed
CN-102020865-B Method for manufacturing grey dye by utilizing 1-amino anthraquinone production waste residues JIANGSU YABANG DYE CO LTD 2013-04-10 CN disclosed
CN-102020865-A Method for manufacturing grey dye by utilizing 1-amino anthraquinone production waste residues JIANGSU YABANG DYE CO LTD 2011-04-20 CN disclosed
CN-102020864-A Method for manufacturing yellow dye by utilizing 1-amino anthraquinone production waste residues JIANGSU YABANG DYE CO LTD 2011-04-20 CN disclosed
EP-0439585-B1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS MAG GEORG MAYRHOFER & CO OHG (AT) 1997-10-29 EP disclosed
US-5196478-A Polystyrene, assays EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) 1993-03-23 US disclosed
EP-0090278-A1 Process for the preparation of anthrimide carbazole dyes BAYER AG (DE) 1983-10-05 EP disclosed
EP-0057381-A2 Trisanthraquinonylaminotriazine compounds as well as their preparation and application as vat dyes BAYER AG (DE) 1982-08-11 EP disclosed
EP-0057375-A2 Vat dyes of the trisanthraquinonylaminotriazine series as well as their preparation BAYER AG (DE) 1982-08-11 EP disclosed
US-4329456-A ACYLATION WITHOUT INTERMEDIATE ISOLATION CIBA-GEIGY AG (CH) 1982-05-11 US disclosed
US-4265633-A Process for the manufacture of vat dyes CIBA-GEIGY AG (CH) 1981-05-05 US disclosed
EP-0025166-A1 Process for preparing vat dyestuffs of the anthraquinone series, their use in dyeing and printing preparations and in dyeing and printing CIBA-GEIGY AG (CH) 1981-03-18 EP disclosed
EP-0019285-A1 Process for preparing asymmetrical vat dyestuffs of the anthraquinone series and their use in dyeing and printing CIBA-GEIGY AG (CH) 1980-11-26 EP disclosed
US-4213909-A Process for the preparation of 1-amino-4-bromoanthraquinone-2-sulfonic acid II BAYER AKTIENGESELLSCHAFT (DE) 1980-07-22 US disclosed