SCHEMBL8777749

SCHEMBL8777749

Cc1cc(S)n2cnnc2n1

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.67
MAPT P10636 6/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
POLB P06746 2/20 0.43
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19090628 0.80 KDM4E (1.00) KDM4EMAPTSMN1; SMN2POLBGAA
SCHEMBL5145529 0.77 KDM4E (0.67) KDM4EMAPTSMN1; SMN2POLBGAA
SCHEMBL10163634 0.74 KDM4E (0.62) KDM4EMAPTSMN1; SMN2POLBGAA
SCHEMBL10164373 0.73 KDM4E (0.61) KDM4EMAPTSMN1; SMN2POLBGAA
SCHEMBL10164377 0.72 KDM4E (0.59) KDM4EMAPTSMN1; SMN2POLBGAA
SCHEMBL9679665 0.71 CYP1A2 (0.42) KDM4EMAPTSMN1; SMN2POLBGAA
SCHEMBL9329531 0.69 PDE2A (0.37) KDM4EGAA
SCHEMBL8253238 0.68 KDM4E (0.54) KDM4EMAPTSMN1; SMN2GAA
SCHEMBL10407465 0.65 HSD17B10 (0.50) KDM4EMAPTSMN1; SMN2POLBGAA
SCHEMBL6261617 0.64 ALDH1A1 (0.45) SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0534283-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1997-12-17 EP disclosed
US-5580713-A EXHIBITS GREAT INTERIMAGE EFFECT AND SMALL DEPENDENCY ON CHANGES IN DEVELOPING PROCESS FACTORS FUJI PHOTO FILM CO., LTD. (JP) 1996-12-03 US disclosed
US-5437968-A Having improved push-processing suitability; emulsion layers containing yellow colloidal silver; development inhibitor component FUJI PHOTO FILM CO., LTD. (JP) 1995-08-01 US disclosed
US-5290676-A Methine dye sensitizers, controlling size and shape of silver halide grains FUJI PHOTO FILM CO., LTD. (JP) 1994-03-01 US disclosed
EP-0534283-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-03-31 EP disclosed