SCHEMBL8777770

SCHEMBL8777770

Nc1cccc2c1C(=O)c1cccc(O)c1C2=O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.76
ADORA2A P29274 2/20 0.68
MAPT P10636 7/20 0.67
TDP1 Q9NUW8 5/20 0.67
ALDH1A1 P00352 4/20 0.67
MAPK1 P28482 4/20 0.67
HPGD P15428 3/20 0.67
SMN1; SMN2 Q16637 3/20 0.67
LMNA P02545 2/20 0.67
TSHR P16473 2/20 0.67
ALOX15 P16050 2/20 0.67
HSD17B10 Q99714 2/20 0.67
MAOB P27338 1/20 0.67
HTT P42858 1/20 0.67
STAT3 P40763 1/20 0.62
KMT2A Q03164 6/20 0.61
MEN1 O00255 5/20 0.61
POLB P06746 4/20 0.61
CSNK1A1 P48729 2/20 0.61
CSNK1D P48730 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Hydroxyanthraquinone SCHEMBL11333211 0.94 ADORA2A (0.79) MAOAADORA2AMAPTTDP1ALDH1A1
SCHEMBL10871531 0.94 MAPT (0.77) MAOAADORA2AMAPTTDP1ALDH1A1
SCHEMBL29441199 0.90 MEN1 (0.70) MAOAADORA2AMAPTTDP1ALDH1A1
SCHEMBL8519860 0.90 MEN1 (0.70) MAOAADORA2AMAPTTDP1ALDH1A1
Hydrochloric Acid SCHEMBL5400530 0.89 MEN1 (0.68) MAOAADORA2AMAPTTDP1ALDH1A1
Anthrarufin SCHEMBL29363946 0.87 MAOA (1.00) MAOAMAPTTDP1ALDH1A1MAPK1
Anthrarufin SCHEMBL187843 0.87 MAOA (1.00) MAOAMAPTTDP1ALDH1A1MAPK1
SCHEMBL64318 0.87 ADORA2A (0.86) MAOAADORA2AMAPTTDP1ALDH1A1
Anthrarufin SCHEMBL29874705 0.87 MAOA (1.00) MAOAMAPTTDP1ALDH1A1MAPK1
SCHEMBL29944895 0.87 ADORA2A (0.86) MAOAADORA2AMAPTTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-4036859-A Method for the preparation of 2-hydroxybenzanthrone compounds MONTEDISON FIBRE S.P.A. (IT) 1977-07-19 US claimed
EP-4713308-A2 IMPROVED PRODUCTION OF REACTION PRODUCTS FROM AN ELECTROSYNTHETIC REACTION Quino Energy, Inc. (US) 2026-03-25 EP disclosed
WO-2024242934-A9 IMPROVED PRODUCTION OF REACTION PRODUCTS FROM AN ELECTROSYNTHETIC REACTION QUINO ENERGY, INC. (US) 2025-01-30 WO disclosed
WO-2024242934-A2 IMPROVED PRODUCTION OF REACTION PRODUCTS FROM AN ELECTROSYNTHETIC REACTION QUINO ENERGY, INC. (US) 2024-11-28 WO disclosed
EP-2859051-B1 ANTHRAQUINONE AZO DYES HUNTSMAN ADV MAT SWITZERLAND (CH) 2019-04-17 EP disclosed
CN-104350105-B anthraquinone azo dyes 亨斯迈先进材料(瑞士)有限公司 2017-05-24 CN disclosed
CN-104350105-A Anthraquinone azo dyes HUNTSMAN ADV MAT SWITZERLAND 2015-02-11 CN disclosed
EP-0585873-B1 Method of preparing disazo pigments CLARIANT GMBH (DE) 1997-12-29 EP disclosed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed
US-4246401-A Axomethine pigments BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
EP-0018538-A2 Anthraquinone derivatives, process for their preparation, process for the pigmentation of organic macromolecular materials and pigmented organic macromolecular material BAYER AG (DE) 1980-11-12 EP disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
EP-0008627-A2 Quinazoline derivatives, azo dyes derived from the quinazolines and their use as pigments BAYER AG (DE) 1980-03-19 EP disclosed
EP-0008063-A1 Azomethine derivatives of anthraquinones, methods for their preparation, their use in the pigmentation of organic macromolecular compounds and the materials thus obtained BAYER AG (DE) 1980-02-20 EP disclosed
US-4065478-A Process for the manufacture of α,α'-aminonitroanthraquinones CIBA-GEIGY AG (CH) 1977-12-27 US disclosed
US-4036859-A Method for the preparation of 2-hydroxybenzanthrone compounds MONTEDISON FIBRE S.P.A. (IT) 1977-07-19 US disclosed
US-3971812-A Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3939113-A ANTHRAQUINONE DYES CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed