Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777918 | 0.90 | P2RY1 (0.54) | P2RY1EPHX2KMT2AEPHX1ALDH1A1 | |
| SCHEMBL8777810 | 0.87 | EPHX2 (0.48) | P2RY1EPHX2EPHX1ALDH1A1HTT | |
| SCHEMBL8777969 | 0.74 | EPHX2 (0.52) | P2RY1EPHX2KMT2AEPHX1ALDH1A1 | |
| SCHEMBL4212390 | 0.74 | EPHX1 (0.61) | EPHX2KMT2AEPHX1ALDH1A1HTT | |
| SCHEMBL6442708 | 0.72 | EPHX1 (0.73) | EPHX2EPHX1ALDH1A1HTTPOLB | |
| SCHEMBL11876262 | 0.72 | PTGS1 (0.50) | KMT2AALDH1A1 | |
| SCHEMBL1021857 | 0.71 | MGLL (0.44) | MGLL | |
| SCHEMBL8777887 | 0.70 | EPHX2 (0.47) | P2RY1EPHX2EPHX1ALDH1A1HTT | |
| SCHEMBL11881050 | 0.69 | SMN1; SMN2 (0.48) | KMT2AALDH1A1MGLL | |
| SCHEMBL4137732 | 0.69 | EPHX2 (0.81) | EPHX2KMT2AEPHX1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665216-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5576335-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0665216-A1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |