Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 8/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Juarezic Acid SCHEMBL15064809 | 0.92 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9817383 | 0.88 | MAOB (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8948870 | 0.88 | MAOB (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7159537 | 0.88 | MAOB (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Juarezic Acid SCHEMBL417723 | 0.88 | HDAC3 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Fumaric Acid SCHEMBL11411218 | 0.87 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Maleic Acid SCHEMBL5709281 | 0.87 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Fumaric Acid SCHEMBL11415463 | 0.87 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Acrylic Acid SCHEMBL11151829 | 0.85 | MCL1 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Juarezic Acid SCHEMBL2246623 | 0.85 | HDAC3 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587139-B1 | Heat-sensitive recording sheet | MITSUBISHI PAPER MILLS LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5427996-A | Protective surface layer composed of latex; chemical, water resistant, storage stability | MITSUBISHI PAPER MILLS LIMITED (JP) | 1995-06-27 | — | — | US | disclosed |
| EP-0587139-A2 | Heat-sensitive recording sheet | MITSUBISHI PAPER MILLS, LTD. (JP) | 1994-03-16 | — | — | EP | disclosed |