Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065834 | 0.87 | KMT2A (0.65) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8647576 | 0.86 | KMT2A (0.60) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8647579 | 0.86 | KMT2A (0.60) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8775364 | 0.84 | KMT2A (0.61) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8775496 | 0.82 | KMT2A (0.58) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL7758627 | 0.81 | CHRM1 (0.72) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL7760568 | 0.81 | KMT2A (0.57) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL7755543 | 0.80 | KMT2A (0.69) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8775322 | 0.79 | CHRM1 (0.59) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8685481 | 0.79 | KMT2A (0.58) | KMT2ACHRM1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569564-B1 | BIPHENYLYLQUINUCLIDINES, USEFUL AS SQUALENE SYNTHETASE INHIBITORS | ZENECA LTD (GB) | 1997-12-29 | — | — | EP | claimed |
| EP-0569564-A1 | BIPHENYLYLQUINUCLIDINES, USEFUL AS SQUALENE SYNTHETASE INHIBITORS | ZENECA LIMITED (GB) | 1993-11-18 | — | — | EP | claimed |
| WO-1993009115-A1 | BIPHENYLYLQUINUCLIDINES, USEFUL AS SQUALENE SYNTHETASE INHIBITORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-13 | — | — | WO | claimed |