SCHEMBL8777935

SCHEMBL8777935

OCCOC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5538297 0.98 THRB (0.31)
SCHEMBL7563976 0.98 THRB (0.31)
SCHEMBL28016008 0.98 THRB (0.31)
SCHEMBL12368530 0.92 TSHR (0.32) TSHRMAPK1
SCHEMBL31288478 0.87 MEN1 (0.46) TSHRMAPK1
SCHEMBL31288640 0.87 MEN1 (0.46) TSHRMAPK1
SCHEMBL31288480 0.87 MEN1 (0.46) TSHRMAPK1
SCHEMBL31288475 0.87 MEN1 (0.46) TSHRMAPK1
SCHEMBL31312525 0.85 MEN1 (0.44) TSHRMAPK1
SCHEMBL7560047 0.85 MEN1 (0.44) TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111909128-B Ethylene sulfite derivative and preparation method and application thereof 华南师范大学 2023-01-10 CN disclosed
CN-111909128-A Ethylene sulfite derivative and preparation method and application thereof 华南师范大学 2020-11-10 CN disclosed
EP-0701986-B1 Process for production of unsaturated ether and catalyst used for production of unsaturated ether NIPPON CATALYTIC CHEM IND (JP) 1997-12-29 EP disclosed
US-5650544-A Process for production of unsaturated ether and catalyst used for production of unsaturated ether NIPPON SHOKUBAI CO., LTD. (JP) 1997-07-22 US disclosed
EP-0701986-A1 Process for production of unsaturated ether and catalyst used for production of unsaturated ether NIPPON SHOKUBAI CO., LTD. (JP) 1996-03-20 EP disclosed