Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.80 |
| ▸ | EPHX1 | P07099 | 11/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13296457 | 0.94 | EPHX2 (0.71) | EPHX2EPHX1ALDH1A1HTTMEN1 | |
| SCHEMBL11619645 | 0.88 | KMT2A (0.76) | EPHX2EPHX1ALDH1A1HTTMEN1 | |
| SCHEMBL11798035 | 0.88 | EPHX2 (0.63) | EPHX2EPHX1ALDH1A1HTTMEN1 | |
| SCHEMBL4348602 | 0.87 | EPHX2 (0.74) | EPHX2EPHX1ALDH1A1HTTMEN1 | |
| SCHEMBL11033138 | 0.85 | EPHX1 (0.84) | EPHX2EPHX1ALDH1A1HTT | |
| SCHEMBL11034317 | 0.85 | EPHX1 (0.84) | EPHX2EPHX1ALDH1A1HTT | |
| SCHEMBL6438783 | 0.85 | EPHX1 (0.84) | EPHX2EPHX1ALDH1A1HTT | |
| SCHEMBL15741892 | 0.84 | EPHX1 (0.66) | EPHX2EPHX1ALDH1A1HTTMEN1 | |
| SCHEMBL8602435 | 0.84 | EPHX2 (0.69) | EPHX2EPHX1ALDH1A1HTTMEN1 | |
| SCHEMBL8602439 | 0.84 | EPHX2 (0.69) | EPHX2EPHX1ALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665216-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5576335-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0665216-A1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |