SCHEMBL8778094

SCHEMBL8778094

CCC[Si](O)(CCC)CCC.[LiH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL619037 0.96
SCHEMBL28586448 0.92
SCHEMBL28586460 0.92
SCHEMBL6514982 0.86
SCHEMBL3482195 0.83 TSHR (0.35)
SCHEMBL3482286 0.83 TSHR (0.35)
SCHEMBL1988893 0.81
SCHEMBL3481902 0.81
SCHEMBL8778115 0.79 TSHR (0.38)
SCHEMBL272672 0.74 TSHR (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188224-A1 METHOD FOR PRODUCING ONE-TERMINAL FUNCTIONAL ORGANOPOLYSILOXANE AND ONE-TERMINAL FUNCTIONAL ORGANOPOLYSILOXANE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-06-12 US disclosed
EP-4506393-A1 METHOD FOR PRODUCING ONE-END-FUNCTIONAL ORGANOPOLYSILOXANE AND ONE-END-FUNCTIONAL ORGANOPOLYSILOXANE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-02-12 EP disclosed
WO-2023195358-A1 METHOD FOR PRODUCING ONE-END-FUNCTIONAL ORGANOPOLYSILOXANE AND ONE-END-FUNCTIONAL ORGANOPOLYSILOXANE COMPOSITION 信越化学工業株式会社 2023-10-12 WO disclosed
US-20220176016-A1 IMPLANT MATERIAL CONTAINING SURFACE-TREATED AROMATIC POLYETHER KETONE AND MANUFACTURING METHOD THEREFOR NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) 2022-06-09 US disclosed
CN-113631125-A Implant material containing surface-treated aromatic polyether ketone and method for producing same 国立大学法人冈山大学 2021-11-09 CN disclosed
EP-0814111-A1 Process for producing diorganopolysiloxane Chisso Corporation (JP) 1997-12-29 EP disclosed
US-5672671-A ANIONIC LIVING POLYMERIZATION OF A MIXTURE OF CYCLIC SILOXANE AND A PREVIOUSLY ACETYLATED POLYSILOXANE(WHICH HAD TWO SILANOL END GROUPS) USING LITHIUM COMPOUND AS INITIATOR, FOR NARRAOW MOLECULAR WEIGHT DISTRIBUTION, FEW BY-PRODUCTS CHISSO CORPORATION (JP) 1997-09-30 US disclosed