SCHEMBL8778268

SCHEMBL8778268

CC1CC(CS)CNC1CC(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8778223 0.77 FDPS (0.38) FDPS
SCHEMBL8778296 0.77 FDPS (0.36) FDPS
SCHEMBL8778222 0.74 FDPS (0.38) FDPS
SCHEMBL8778275 0.72
SCHEMBL8778148 0.65 FDPS (0.33) FDPS
SCHEMBL8778339 0.63 FDPS (0.36) FDPS
SCHEMBL8778254 0.62 FDPS (0.38) FDPS
SCHEMBL8778316 0.61 FDPS (0.48) FDPS
SCHEMBL8778313 0.60 KDM4E (0.31) FDPS
SCHEMBL8778356 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648120-B1 USE OF PHOSPHONATES FOR THE TREATMENT OF OSTEOPOROSIS PROCTER & GAMBLE PHARMA (US) 1997-12-29 EP claimed
EP-0648120-B1 USE OF PHOSPHONATES FOR THE TREATMENT OF OSTEOPOROSIS PROCTER & GAMBLE PHARMA (US) 1997-12-29 EP disclosed
WO-1994000130-A1 COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) 1994-01-06 WO disclosed