Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 3/20 | 0.35 |
| ▸ | CPA3 | P15088 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6714136 | 0.88 | CYP1A2 (0.42) | HMGB1CXCL12CYP1A2 | |
| SCHEMBL9972723 | 0.88 | CYP1A2 (0.50) | HMGB1CXCL12CYP1A2SIRT5NR3C1 | |
| SCHEMBL201844 | 0.81 | HMGCR (0.47) | CYP1A2TDP1 | |
| SCHEMBL2026376 | 0.78 | HMGB1 (0.39) | HMGB1CXCL12CYP1A2NR3C1PGR | |
| SCHEMBL7211982 | 0.76 | PPARG (0.40) | CYP1A2TDP1 | |
| SCHEMBL10024350 | 0.75 | KDM6B (0.53) | HMGB1CXCL12CYP1A2SIRT5NR3C1 | |
| SCHEMBL9972708 | 0.75 | HMGB1 (0.46) | HMGB1CXCL12CYP1A2SIRT5NR3C1 | |
| SCHEMBL17491250 | 0.75 | PTGES (0.47) | ESR1FOLH1 | |
| SCHEMBL17491351 | 0.75 | PTGES (0.47) | ESR1FOLH1 | |
| SCHEMBL17491186 | 0.75 | PTGES (0.47) | ESR1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812369-A1 | POLYESTER FIBRES OR THREADS WITH HIGH PILL RESISTANCE | AKZO NOBEL N.V. (NL) | 1997-12-17 | — | — | EP | claimed |
| WO-1996027037-A1 | POLYESTER FIBRES OR THREADS WITH HIGH PILL RESISTANCE | AKZO NOBEL N.V. (NL) | 1996-09-06 | — | — | WO | claimed |