Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP3 | P08254 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8755186 | 0.85 | HPGD (0.59) | POLBLMNAHPGD | |
| SCHEMBL12294114 | 0.85 | HPGD (0.59) | POLBLMNAHPGD | |
| SCHEMBL10078884 | 0.79 | TSHR (0.49) | TSHRSMN1; SMN2HPGDMEN1HTT | |
| SCHEMBL24780326 | 0.74 | CHRNB2 (0.53) | — | |
| SCHEMBL11904821 | 0.73 | SMN1; SMN2 (0.51) | POLBLMNACNR2TSHRSMN1; SMN2 | |
| SCHEMBL18896343 | 0.73 | POLB (0.69) | POLBLMNACNR2HPGDMEN1 | |
| SCHEMBL13273976 | 0.72 | HPGD (0.45) | NPC1RAB9AHPGD | |
| SCHEMBL11904837 | 0.72 | SMN1; SMN2 (0.53) | POLBLMNACNR2TSHRSMN1; SMN2 | |
| SCHEMBL28421638 | 0.72 | PLA2G2C (0.44) | PRSS1CTSGCTRB1CMA1NPC1 | |
| SCHEMBL8331572 | 0.72 | NPC1 (0.61) | POLBLMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813542-A1 | AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-12-29 | — | — | EP | disclosed |