SCHEMBL8778482

SCHEMBL8778482

O=C1CCOCCN1C(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.54
TSHR P16473 1/20 0.54
LMNA P02545 1/20 0.49
NAAA Q02083 2/20 0.48
FAAH O00519 2/20 0.48
GAA P10253 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 5/20 0.47
PHGDH O43175 1/20 0.46
MAPT P10636 2/20 0.45
KMT2A Q03164 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8778553 0.85 HPGD (0.51) HPGDTSHRLMNANAAAFAAH
SCHEMBL7338840 0.83 ALDH1A1 (0.61) HPGDNAAASMN1; SMN2ALDH1A1MAPT
SCHEMBL1002469 0.80 CYP1A2 (0.64) HPGDLMNASMN1; SMN2ALDH1A1MAPT
Water SCHEMBL27387795 0.78 CYP1A2 (0.62) HPGDLMNASMN1; SMN2ALDH1A1MAPT
SCHEMBL6960124 0.78 SMN1; SMN2 (0.63) HPGDSMN1; SMN2ALDH1A1MAPTKMT2A
SCHEMBL2461680 0.77 SMN1; SMN2 (0.37) HPGDLMNAGAASMN1; SMN2ALDH1A1
SCHEMBL9874977 0.77 SMN1; SMN2 (0.66) HPGDSMN1; SMN2ALDH1A1MAPTKMT2A
SCHEMBL8380782 0.77 SMN1; SMN2 (0.66) HPGDSMN1; SMN2ALDH1A1MAPTKMT2A
SCHEMBL151854 0.77 SMN1; SMN2 (0.66) HPGDSMN1; SMN2ALDH1A1MAPTKMT2A
SCHEMBL8380683 0.77 SMN1; SMN2 (0.66) HPGDSMN1; SMN2ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1177975-A Bleaching compositions and additives comprising bleach activators having alpha-modified lactam leaving groups PROCTER & GAMBLE SOMPANY (US) 1998-04-01 CN disclosed
EP-0804530-A1 BLEACHING COMPOSITIONS AND ADDITIVES COMPRISING BLEACH ACTIVATORS HAVING ALPHA-MODIFIED LACTAM LEAVING-GROUPS THE PROCTER & GAMBLE COMPANY (US) 1997-11-05 EP disclosed
US-5635103-A Bleaching compositions and additives comprising bleach activators having alpha-modified lactam leaving-groups THE PROCTER & GAMBLE COMPANY (US) 1997-06-03 US disclosed
WO-1996022350-A1 BLEACHING COMPOSITIONS AND ADDITIVES COMPRISING BLEACH ACTIVATORS HAVING ALPHA-MODIFIED LACTAM LEAVING-GROUPS THE PROCTER & GAMBLE COMPANY (US) 1996-07-25 WO disclosed