Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.67 |
| ▸ | HTR1B | P28222 | 9/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.57 |
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.56 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1534891 | 1.00 | KCNA3 (0.67) | KCNA3HTR1BSLC6A4HRH1HRH3 | |
| SCHEMBL95124 | 1.00 | KCNA3 (0.67) | KCNA3HTR1BSLC6A4HRH1HRH3 | |
| SCHEMBL7633057 | 0.98 | KCNA3 (0.69) | KCNA3HTR1BSLC6A4HRH1HRH3 | |
| SCHEMBL97164 | 0.93 | HTR1B (0.68) | KCNA3HTR1BSLC6A4HRH1TDP1 | |
| SCHEMBL16902840 | 0.91 | KCNA3 (0.79) | KCNA3HTR1BSLC6A4HRH1HRH3 | |
| SCHEMBL16902852 | 0.91 | KCNA3 (0.79) | KCNA3HTR1BSLC6A4HRH1HRH3 | |
| SCHEMBL16902849 | 0.91 | KCNA3 (0.79) | KCNA3HTR1BSLC6A4HRH1HRH3 | |
| SCHEMBL16902853 | 0.91 | KCNA3 (0.79) | KCNA3HTR1BSLC6A4HRH1HRH3 | |
| SCHEMBL16902854 | 0.91 | KCNA3 (0.79) | KCNA3HTR1BSLC6A4HRH1HRH3 | |
| SCHEMBL16902855 | 0.91 | KCNA3 (0.79) | KCNA3HTR1BSLC6A4HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |