Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011602 | 0.91 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1NPC1RAB9ANFKB1 | |
| SCHEMBL9011659 | 0.91 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1NPC1RAB9ANFKB1 | |
| SCHEMBL9011867 | 0.89 | SMN1; SMN2 (0.59) | SMN1; SMN2L3MBTL1NPC1RAB9ANFKB1 | |
| SCHEMBL7314937 | 0.87 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL1NPC1RAB9ANFKB1 | |
| SCHEMBL13308494 | 0.84 | ESR1 (0.56) | SMN1; SMN2L3MBTL1NPC1RAB9ANFKB1 | |
| SCHEMBL14382370 | 0.84 | ESR1 (0.56) | SMN1; SMN2L3MBTL1NPC1RAB9ANFKB1 | |
| SCHEMBL14015788 | 0.84 | ESR1 (0.56) | SMN1; SMN2L3MBTL1NPC1RAB9ANFKB1 | |
| SCHEMBL11956138 | 0.84 | ESR1 (0.56) | SMN1; SMN2L3MBTL1NPC1RAB9ANFKB1 | |
| SCHEMBL17484853 | 0.84 | ESR1 (0.56) | SMN1; SMN2L3MBTL1NPC1RAB9ANFKB1 | |
| SCHEMBL2713160 | 0.84 | ESR1 (0.56) | SMN1; SMN2L3MBTL1NPC1RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |