Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891407 | 0.87 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL8778545 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL9011867 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL5672183 | 0.84 | TSHR (0.59) | SMN1; SMN2L3MBTL1KMT2ARAB9AHPGD | |
| SCHEMBL293026 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL9011659 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL9011602 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL8640378 | 0.82 | HTR1A (0.63) | SMN1; SMN2L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL11790 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL6480994 | 0.81 | KDM4E (0.39) | SMN1; SMN2L3MBTL1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918074-A | CALCIUM ANTAGONISTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0217142-A2 | A polyazaheterocyclic compound | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-04-08 | — | — | EP | disclosed |