Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LSS | P48449 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3024482 | 1.00 | HRH3 (0.60) | HRH3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL367677 | 0.98 | HRH3 (0.57) | HRH3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL9654053 | 0.93 | HRH3 (0.54) | HRH3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL7475821 | 0.93 | DRD2 (0.58) | HRH3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL7788133 | 0.91 | HRH3 (0.52) | HRH3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL5390369 | 0.91 | HRH3 (0.69) | HRH3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL10559291 | 0.91 | HRH3 (0.69) | HRH3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL10554981 | 0.91 | HRH3 (0.69) | HRH3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL10558691 | 0.91 | HRH3 (0.69) | HRH3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL10556391 | 0.91 | HRH3 (0.69) | HRH3DRD2DRD4DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |