Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5258185 | 0.86 | DRD2 (0.51) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL17637581 | 0.84 | DRD2 (0.61) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL9252588 | 0.83 | NR5A1 (0.56) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL11375096 | 0.83 | NR5A1 (0.56) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL14015787 | 0.83 | NR5A1 (0.56) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL11369041 | 0.83 | NR5A1 (0.56) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL3763682 | 0.82 | DRD2 (0.58) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL26118017 | 0.81 | TP53 (0.54) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL8955549 | 0.81 | TP53 (0.54) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL19736015 | 0.81 | DRD2 (0.54) | DRD2DRD4DRD3RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |