Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480437 | 0.87 | ALDH1A1 (0.54) | ALDH1A1LMNATSHRKDM4ECYP2C19 | |
| SCHEMBL8778533 | 0.86 | MAPT (0.53) | ALDH1A1TSHRKDM4ECYP2C19CYP1A2 | |
| SCHEMBL8955786 | 0.84 | ALDH1A1 (0.69) | ALDH1A1LMNATSHRKDM4ECYP2C19 | |
| SCHEMBL10741318 | 0.84 | MAPT (0.54) | ALDH1A1TSHRKDM4ECYP2C19CYP1A2 | |
| SCHEMBL1311060 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNATSHRKDM4ECYP2C19 | |
| SCHEMBL8917491 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNATSHRKDM4ECYP2C19 | |
| SCHEMBL12978667 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNATSHRKDM4ECYP2C19 | |
| SCHEMBL28556250 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNATSHRKDM4ECYP2C19 | |
| SCHEMBL196619 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNATSHRKDM4ECYP2C19 | |
| SCHEMBL1547223 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNATSHRKDM4ECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |