SCHEMBL8778696

SCHEMBL8778696

CCCCCCCCS(=O)(=O)CC

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.65
FAAH O00519 5/20 0.59
CES1 P23141 5/20 0.52
CES2 O00748 2/20 0.52
TSHR P16473 1/20 0.47
THRB P10828 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2288234 1.00 CA2 (0.65) CA2FAAHCES1CES2TSHR
SCHEMBL8778778 1.00 CA2 (0.65) CA2FAAHCES1CES2TSHR
SCHEMBL19322838 1.00 CA2 (0.65) CA2FAAHCES1CES2TSHR
SCHEMBL8778819 1.00 CA2 (0.65) CA2FAAHCES1CES2TSHR
SCHEMBL11107583 1.00 CA2 (0.65) CA2FAAHCES1CES2TSHR
SCHEMBL8778860 1.00 CA2 (0.65) CA2FAAHCES1CES2TSHR
SCHEMBL7134001 0.97 CA2 (0.61) CA2FAAHCES1CES2TSHR
SCHEMBL11058951 0.91 CA2 (0.68) CA2FAAHCES1CES2TSHR
SCHEMBL8778750 0.91 CA2 (0.68) CA2FAAHCES1CES2TSHR
SCHEMBL5586100 0.91 CA2 (0.68) CA2FAAHCES1CES2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300143-A Water soluble dye, sulfone, and amide or cyclic amine XEROX CORPORATION (US) 1994-04-05 US claimed
US-10654845-B2 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-05-19 US disclosed
US-20180016273-A1 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-01-18 US disclosed
US-7199265-B2 Thyroid receptor ligands, pharmaceutical compositions comprising them and their use in the treatment of disorders influenced by thyroid hormones KARO BIO AB (SE) 2007-04-03 US disclosed
EP-0602914-B1 Ink compositions for ink jet printing XEROX CORP (US) 1997-11-12 EP disclosed
EP-0602914-A1 Ink compositions for ink jet printing XEROX CORPORATION (US) 1994-06-22 EP disclosed
US-5300143-A Water soluble dye, sulfone, and amide or cyclic amine XEROX CORPORATION (US) 1994-04-05 US disclosed
US-5110902-A High molecular weight polythioether-sulfones PHILLIPS PETROLEUM COMPANY (US) 1992-05-05 US disclosed
US-5086163-A High molecular weight polymers formed by contacting dihaloaromatic sulfone with complex of alkali metal aminoalkanoate and alkalimetal hydrosulfide PHILLIPS PETROLEUM COMPANY (US) 1992-02-04 US disclosed
US-5015725-A Heat resistant thermoplastic resins for electrical components, aircraft or automobile parts, protective coatings PHILLIPS PETROLEUM COMPANY (US) 1991-05-14 US disclosed
EP-0309955-A1 Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1989-04-05 EP disclosed
US-4125525-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-11-14 US disclosed
US-4086079-A FOR FRUIT BEARING PLANTS THE PROCTER & GAMBLE COMPANY (US) 1978-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180016273-A1 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES CYP4B1, CYP1B1, CYP8B1 CA2 1448/4885FAAH 91/4885CES1 123/4885
US-10654845-B2 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides CYP4B1, CYP1B1, CYP8B1 CA2 1679/4885FAAH 114/4885CES1 128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.