Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9102994 | 1.00 | KEAP1 (0.59) | KEAP1NFE2L2EPHX2ALDH1A1TP53 | |
| SCHEMBL9101224 | 1.00 | KEAP1 (0.59) | KEAP1NFE2L2EPHX2ALDH1A1TP53 | |
| SCHEMBL9099940 | 1.00 | KEAP1 (0.59) | KEAP1NFE2L2EPHX2ALDH1A1TP53 | |
| SCHEMBL3683856 | 1.00 | KEAP1 (0.59) | KEAP1NFE2L2EPHX2ALDH1A1TP53 | |
| SCHEMBL8778703 | 1.00 | KEAP1 (0.59) | KEAP1NFE2L2EPHX2ALDH1A1TP53 | |
| SCHEMBL8778811 | 1.00 | KEAP1 (0.59) | KEAP1NFE2L2EPHX2ALDH1A1TP53 | |
| SCHEMBL8778823 | 1.00 | KEAP1 (0.59) | KEAP1NFE2L2EPHX2ALDH1A1TP53 | |
| SCHEMBL9099317 | 1.00 | KEAP1 (0.59) | KEAP1NFE2L2EPHX2ALDH1A1TP53 | |
| SCHEMBL8778827 | 0.98 | KEAP1 (0.60) | KEAP1NFE2L2EPHX2ALDH1A1TP53 | |
| SCHEMBL1911906 | 0.93 | KEAP1 (0.58) | KEAP1NFE2L2EPHX2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300143-A | Water soluble dye, sulfone, and amide or cyclic amine | XEROX CORPORATION (US) | 1994-04-05 | — | — | US | claimed |
| EP-0602914-B1 | Ink compositions for ink jet printing | XEROX CORP (US) | 1997-11-12 | — | — | EP | disclosed |
| US-5517350-A | Optical component based on Langmuir-Blodgett layers | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |
| EP-0602914-A1 | Ink compositions for ink jet printing | XEROX CORPORATION (US) | 1994-06-22 | — | — | EP | disclosed |
| US-5300143-A | Water soluble dye, sulfone, and amide or cyclic amine | XEROX CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |