Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisperimus SCHEMBL8778895 | 1.00 | NPY4R (0.36) | NPY4RS1PR1S1PR3S1PR2S1PR5 | |
| Anisperimus SCHEMBL8923118 | 1.00 | NPY4R (0.36) | NPY4RS1PR1S1PR3S1PR2S1PR5 | |
| Anisperimus SCHEMBL8778901 | 0.92 | FAAH (0.39) | FAAHMAOAMAOBHDAC3HDAC4 | |
| Anisperimus SCHEMBL8778912 | 0.92 | FAAH (0.39) | FAAHMAOAMAOBHDAC3HDAC4 | |
| Anisperimus SCHEMBL8778920 | 0.92 | FAAH (0.39) | FAAHMAOAMAOBHDAC3HDAC4 | |
| Trifluoroacetic Acid SCHEMBL8919616 | 0.88 | NPY4R (0.39) | NPY4RS1PR1S1PR3S1PR2S1PR5 | |
| Trifluoroacetic Acid SCHEMBL8921920 | 0.88 | NPY4R (0.39) | NPY4RS1PR1S1PR3S1PR2S1PR5 | |
| Trifluoroacetic Acid SCHEMBL8919832 | 0.88 | NPY4R (0.39) | NPY4RS1PR1S1PR3S1PR2S1PR5 | |
| Trifluoroacetic Acid SCHEMBL9178492 | 0.86 | HDAC6 (0.43) | NPY4RFAAHMAOAMAOBHDAC3 | |
| Tresperimus SCHEMBL9173994 | 0.86 | HDAC6 (0.43) | NPY4RFAAHMAOAMAOBHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669316-B1 | Analogs of 15-deoxyspergualine, process for their preparation and their use as immunosuppressive agents | FOURNIER IND & SANTE (FR) | 1997-07-30 | — | — | EP | claimed |
| US-5637613-A | ANTITUMOR AGENT; IMMUNOSUPPRESSANTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-06-10 | — | — | US | claimed |
| JP-8041007-A | — | — | None | — | — | JP | disclosed |
| US-5637613-A | ANTITUMOR AGENT; IMMUNOSUPPRESSANTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-06-10 | — | — | US | disclosed |
| JP-H0841007-A | 15-DEOXYSPERGUALIN ANALOG, ITS PRODUCTION AND THERAPEUTIC USE | FOURNIER IND & SANTE | 1996-02-13 | — | — | JP | disclosed |