Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442739 | 0.78 | CHRM1 (0.49) | CHRM1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL7847876 | 0.76 | CHRM1 (0.50) | CHRM1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL8441053 | 0.75 | CHRM1 (0.44) | CHRM1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL7852241 | 0.74 | CHRM1 (0.45) | CHRM1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL8316187 | 0.73 | CHRM1 (0.42) | CHRM1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL7851759 | 0.72 | CHRM1 (0.51) | CHRM1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL7893440 | 0.71 | CHRM1 (0.43) | CHRM1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL8081439 | 0.69 | CHRM1 (0.53) | CHRM1HRH3 | |
| SCHEMBL28311734 | 0.68 | KDM4E (0.49) | CHRM2ADRA2AHTR2BSLC6A3 | |
| SCHEMBL18428431 | 0.67 | THRA (0.40) | CHRM1CHRM2CHRM4HTR1ACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621272-B1 | 3,4-Dioxy-1,2,5-thiadiazoles partly useful as fungicides | TOSOH CORP (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-5478849-A | Thiadiazole derivative, process for producing it and agricultural and horticultural fungicide using it as an active ingredient | TOSOH CORPORATION (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0621272-A1 | 3,4-Dioxy-1,2,5-thiadiazoles partly useful as fungicides | Tosoh Corporation (JP) | 1994-10-26 | — | — | EP | disclosed |