Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.67 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.49 |
| ▸ | NQO2 | P16083 | 4/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295837 | 0.84 | ACHE (0.73) | ACHE | |
| SCHEMBL3295844 | 0.84 | ACHE (0.73) | ACHE | |
| Hydrochloric Acid SCHEMBL3299263 | 0.83 | ACHE (0.75) | ACHE | |
| SCHEMBL13407540 | 0.81 | ACHE (0.97) | ACHEMTNR1ANQO2MTNR1B | |
| Methylamine SCHEMBL27747615 | 0.81 | ACHE (0.60) | ACHEMTNR1ANQO2MTNR1B | |
| SCHEMBL269087 | 0.80 | ACHE (0.60) | ACHE | |
| SCHEMBL30563659 | 0.80 | ACHE (0.60) | ACHE | |
| SCHEMBL30563644 | 0.80 | ACHE (0.60) | ACHE | |
| SCHEMBL2463469 | 0.80 | ACHE (0.60) | ACHE | |
| SCHEMBL4418237 | 0.80 | ACHE (0.60) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |