Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.34 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.34 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1278843 | 1.00 | LMNA (0.38) | LMNADNM1HTTMAPTMEN1 | |
| SCHEMBL9239862 | 1.00 | LMNA (0.38) | LMNADNM1HTTMAPTMEN1 | |
| SCHEMBL9243046 | 1.00 | LMNA (0.38) | LMNADNM1HTTMAPTMEN1 | |
| SCHEMBL11791946 | 1.00 | LMNA (0.38) | LMNADNM1HTTMAPTMEN1 | |
| SCHEMBL313592 | 1.00 | LMNA (0.38) | LMNADNM1HTTMAPTMEN1 | |
| SCHEMBL338286 | 1.00 | LMNA (0.38) | LMNADNM1HTTMAPTMEN1 | |
| SCHEMBL11803559 | 0.97 | LMNA (0.36) | LMNADNM1HTTMAPTMEN1 | |
| SCHEMBL5014543 | 0.96 | LMNA (0.41) | LMNADNM1HTTMAPTMEN1 | |
| SCHEMBL16196213 | 0.96 | LMNA (0.41) | LMNADNM1HTTMAPTMEN1 | |
| SCHEMBL4458113 | 0.96 | LMNA (0.41) | LMNADNM1HTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4320445-A | — | — | None | — | — | JP | disclosed |
| EP-0437342-B1 | Method for handling maleimides | NIPPON CATALYTIC CHEM IND (JP) | 1997-03-26 | — | — | EP | disclosed |
| JP-H04320445-A | THERMOPLASTIC POLYESTER RESIN COMPOSITION | ASAHI DENKA KOGYO KK | 1992-11-11 | — | — | JP | disclosed |
| US-5149827-A | In presence of stabilizer at temperature higher than the melting point of maleimide | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0437342-A2 | Method for handling maleimides | NIPPON SHOKUBAI CO., LTD. (JP) | 1991-07-17 | — | — | EP | disclosed |