SCHEMBL8779526

SCHEMBL8779526

C1=CC([Zr]C2C=Cc3ccccc32)c2ccccc21.Cl[Si](Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779616 0.84 HTR2A (0.33) HTR6HTR2A
SCHEMBL29474414 0.84 HTR2A (0.40) HTR6HTR2A
SCHEMBL60674 0.84 HTR2A (0.40) HTR6HTR2A
Chloromethane SCHEMBL3681238 0.82 HTR2A (0.36) HTR6HTR2A
SCHEMBL28278996 0.82 HTR2A (0.39) HTR6HTR2A
Hydrochloric Acid SCHEMBL5838117 0.82 HTR2A (0.39) HTR6HTR2A
Methane SCHEMBL5838564 0.82 HTR2A (0.39) HTR6HTR2A
SCHEMBL27597712 0.82 HTR2A (0.39) HTR6HTR2A
SCHEMBL28300114 0.80 HTR2A (0.35) HTR6HTR2A
Hydrochloric Acid SCHEMBL820050 0.80 HTR2A (0.38) HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0730003-B1 Polypropylene resin composition and molded product TOSOH CORP (JP) 1997-12-29 EP disclosed
US-5608008-A ETHYLENE-A-OLEFIN COPOLYMER ELASTOMER TOSOH CORPORATION (JP) 1997-03-04 US disclosed
EP-0730003-A1 Polypropylene resin composition and molded product Tosoh Corporation (JP) 1996-09-04 EP disclosed