Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 9/20 | 0.43 |
| ▸ | MAOA | P21397 | 8/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12126140 | 0.81 | MAOB (0.57) | MAOBMAOAARCYP11B1CYP11B2 | |
| SCHEMBL15973611 | 0.78 | TSHR (0.45) | MAPTKDM4EHPGDMEN1KMT2A | |
| SCHEMBL6833247 | 0.76 | CYP11B1 (0.46) | MAPTMEN1KMT2AMAOBMAOA | |
| SCHEMBL15716037 | 0.76 | MAOB (0.46) | MAPTMEN1KMT2AMAOBMAOA | |
| SCHEMBL4875399 | 0.76 | MAOA (0.46) | MAPTKDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL6831166 | 0.76 | MAPT (0.40) | MAPTKDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL19095244 | 0.76 | MAOB (0.39) | MAPTMEN1KMT2AMAOBMAOA | |
| SCHEMBL13946937 | 0.76 | MCL1 (0.47) | MAPTMEN1KMT2AMAOBMAOA | |
| SCHEMBL8779810 | 0.76 | KDM4E (0.47) | MAPTKDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL1020460 | 0.73 | TSHR (0.45) | MAPTKDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770599-A1 | PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |