SCHEMBL8779798

SCHEMBL8779798

ClC(Cl)Sc1ccccc1SC(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9018794 0.84 TSHR (0.43) TSHRMAPTNPSR1LMNA
SCHEMBL9018894 0.82 MAPT (0.54) TSHRMEN1MAPTKMT2ANPSR1
SCHEMBL8779777 0.78 CYP1A2 (0.43) TSHRLMNA
SCHEMBL6939635 0.77 CYP1A2 (0.48) TSHRMEN1MAPTKMT2ANPSR1
SCHEMBL8488464 0.75 LMNA (0.35) TSHRMAPTNPSR1LMNA
SCHEMBL8488069 0.73 MAPT (0.45) TSHRMEN1MAPTKMT2ANPSR1
SCHEMBL3911663 0.73 SMN1; SMN2 (0.45) TSHRMAPTLMNA
SCHEMBL8485010 0.71 CYP1A2 (0.36) TSHRMAPTNPSR1LMNA
SCHEMBL14894782 0.71 SMN1; SMN2 (0.43) TSHRMAPTLMNA
SCHEMBL30548758 0.69 MAP2K7 (0.41) MEN1MAPTKMT2ANPSR1APOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770599-A1 PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-05-02 EP disclosed
EP-0742201-A1 PROCESS FOR PRODUCING AROMATIC OR HETEROAROMATIC SULFUR COMPOUNDS SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1996-11-13 EP disclosed