SCHEMBL8779817

SCHEMBL8779817

O=C(NCCCCNC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.79
HDAC2 Q92769 4/20 0.79
HDAC8 Q9BY41 4/20 0.79
HDAC6 Q9UBN7 4/20 0.79
HDAC3 O15379 3/20 0.79
HDAC4 P56524 3/20 0.79
HDAC7 Q8WUI4 3/20 0.79
HDAC10 Q969S8 3/20 0.79
HDAC11 Q96DB2 3/20 0.79
HDAC9 Q9UKV0 3/20 0.79
HDAC5 Q9UQL6 3/20 0.79
NAAA Q02083 1/20 0.79
NPC1 O15118 3/20 0.75
RAB9A P51151 3/20 0.75
GAA P10253 1/20 0.68
SMN1; SMN2 Q16637 3/20 0.66
MAPK1 P28482 1/20 0.66
LMNA P02545 1/20 0.66
POLB P06746 1/20 0.66
EPHX2 P34913 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9452844 0.98 HDAC1 (0.82) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL9489756 0.98 HDAC1 (0.82) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL9188890 0.98 HDAC1 (0.82) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL20734829 0.98 HDAC1 (0.82) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL9492328 0.98 HDAC1 (0.82) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL9492235 0.98 HDAC1 (0.82) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL7460068 0.98 HDAC1 (0.82) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL9489804 0.98 HDAC1 (0.82) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL9491686 0.95 NPC1 (0.75) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL1039449 0.92 HDAC1 (0.69) HDAC1HDAC2HDAC8HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315299-A1 AMIDE COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS FIRMENICH INCORPORATED (US) 2024-09-26 US claimed
CN-102010583-B High-molecular weight long-chain branched crystalline polylactic acid material and preparation method thereof UNIV ZHEJIANG 2012-12-19 CN claimed
CN-102002147-B Melt/solid phase polycondensation preparation method of high molecular weight high crystalline polylactic acid material UNIV ZHEJIANG 2012-05-30 CN claimed
CN-102010583-A High-molecular weight long-chain branched crystalline polylactic acid material and preparation method thereof UNIV ZHEJIANG 2011-04-13 CN claimed
CN-102002147-A Melt/solid-phase polycondensation preparation method of polylactic acid material with high molecular weight and high crystallinity UNIV ZHEJIANG 2011-04-06 CN claimed
US-20240315299-A1 AMIDE COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS FIRMENICH INCORPORATED (US) 2024-09-26 US disclosed
CN-102010583-B High-molecular weight long-chain branched crystalline polylactic acid material and preparation method thereof UNIV ZHEJIANG 2012-12-19 CN disclosed
CN-102002147-B Melt/solid phase polycondensation preparation method of high molecular weight high crystalline polylactic acid material UNIV ZHEJIANG 2012-05-30 CN disclosed
CN-102010583-A High-molecular weight long-chain branched crystalline polylactic acid material and preparation method thereof UNIV ZHEJIANG 2011-04-13 CN disclosed
CN-102002147-A Melt/solid-phase polycondensation preparation method of polylactic acid material with high molecular weight and high crystallinity UNIV ZHEJIANG 2011-04-06 CN disclosed
EP-0470180-B1 HYDROXY-FUNCTIONAL POLY(AMIDE ETHERS) AS THERMOPLASTIC BARRIER RESINS DOW CHEMICAL CO (US) 1997-03-05 EP disclosed
US-5191003-A Diamide compound, improved tire gripping, vibration insulation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-02 US disclosed
US-5143998-A HYDROXY-FUNCTIONAL POLY(AMIDE ETHERS) AS THERMOPLASTIC BARRIER RESINS THE DOW CHEMICAL COMPANY (US) 1992-09-01 US disclosed
US-5089588-A From bisphenol A diglycidyl ether and N,N'-bis/m-hydroxy phenyl)adipamide THE DOW CHEMICAL COMPANY (US) 1992-02-18 US disclosed
EP-0470776-A1 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-02-12 EP disclosed
US-4082749-A FROM CARBOXAMIDES AND ALKALI METAL HYPOCHLORITE, CATALYST BASF AKTIENGESELLSCHAFT (DT) 1978-04-04 US disclosed