Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.45 |
| ▸ | IDO1 | P14902 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779967 | 1.00 | PNMT (0.53) | PNMTTAAR1IGF1RALOX15SIGMAR1 | |
| SCHEMBL15907626 | 0.82 | PNMT (0.53) | PNMTTAAR1SIGMAR1TMEM97IDO1 | |
| SCHEMBL5706583 | 0.81 | PNMT (0.61) | PNMTTAAR1IGF1RALOX15SIGMAR1 | |
| SCHEMBL5706584 | 0.81 | PNMT (0.61) | PNMTTAAR1IGF1RALOX15SIGMAR1 | |
| SCHEMBL7258418 | 0.81 | PNMT (0.61) | PNMTTAAR1IGF1RALOX15SIGMAR1 | |
| SCHEMBL10603412 | 0.81 | PNMT (0.57) | PNMTTAAR1IGF1RALOX15SIGMAR1 | |
| Hydrochloric Acid SCHEMBL14829304 | 0.81 | PNMT (0.52) | PNMTTAAR1SIGMAR1TMEM97IDO1 | |
| Hydrochloric Acid SCHEMBL17045208 | 0.80 | PNMT (0.59) | PNMTTAAR1IGF1RALOX15SIGMAR1 | |
| SCHEMBL18704005 | 0.79 | SLC6A4 (0.52) | TAAR1IGF1RALOX15IDO1 | |
| SCHEMBL22508738 | 0.79 | PNMT (0.48) | PNMTTAAR1IGF1RALOX15SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569276-B1 | Novel use of enantiomers derived from (S)-2-amino-3-(3,4-dichlorobenzyl)-1-propanol | JOUVEINAL INST RECH (FR) | 1997-01-29 | — | — | EP | disclosed |
| EP-0569276-A1 | Novel use of enantiomers derived from (S)-2-amino-3-(3,4-dichlorobenzyl)-1-propanol | INSTITUT DE RECHERCHE JOUVEINAL (I.R.J) (FR) | 1993-11-10 | — | — | EP | disclosed |