Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29642529 | 1.00 | AKR1C3 (0.42) | AKR1C3AKR1C1SMN1; SMN2GAAMAPT | |
| SCHEMBL16582761 | 1.00 | AKR1C3 (0.42) | AKR1C3AKR1C1SMN1; SMN2GAAMAPT | |
| SCHEMBL16568791 | 1.00 | AKR1C3 (0.42) | AKR1C3AKR1C1SMN1; SMN2GAAMAPT | |
| SCHEMBL17997343 | 1.00 | AKR1C3 (0.42) | AKR1C3AKR1C1SMN1; SMN2GAAMAPT | |
| SCHEMBL6568328 | 0.75 | TP53 (0.45) | SMN1; SMN2GAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL16582723 | 0.69 | AKR1C3 (0.36) | AKR1C3AKR1C1GAAMAPTALDH1A1 | |
| SCHEMBL21558150 | 0.69 | AKR1C3 (0.36) | AKR1C3AKR1C1GAAMAPTALDH1A1 | |
| SCHEMBL16582715 | 0.69 | AKR1C3 (0.36) | AKR1C3AKR1C1GAAMAPTALDH1A1 | |
| SCHEMBL8779970 | 0.69 | F2 (0.42) | SMN1; SMN2LMNA | |
| SCHEMBL10843954 | 0.69 | SMN1; SMN2 (0.65) | SMN1; SMN2GAAMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528694-B1 | Method for producing optically active 3-substituted-2-norbornanones and their intermediates | CHISSO CORP (JP) | 1997-04-09 | — | — | EP | disclosed |
| US-5266728-A | Method for producing optically active 3-substituted-2-norbornanones and their intermediates | CHISSO CORPORATION (JP) | 1993-11-30 | — | — | US | disclosed |
| EP-0528694-A2 | Method for producing optically active 3-substituted-2-norbornanones and their intermediates | CHISSO CORPORATION (JP) | 1993-02-24 | — | — | EP | disclosed |