Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26934662 | 1.00 | F2 (0.42) | F2PRSS1CTRB1HSD11B1DDB1 | |
| SCHEMBL7488949 | 0.78 | ALDH1A1 (0.46) | — | |
| SCHEMBL6710847 | 0.77 | LMNA (0.42) | DDB1CRBNLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL11773282 | 0.70 | ALDH1A1 (0.36) | — | |
| SCHEMBL14721191 | 0.70 | ALDH1A1 (0.36) | — | |
| SCHEMBL24587183 | 0.70 | ALDH1A1 (0.36) | — | |
| SCHEMBL8779995 | 0.70 | ALDH1A1 (0.36) | — | |
| SCHEMBL8779972 | 0.69 | AKR1C3 (0.42) | LMNASMN1; SMN2 | |
| SCHEMBL17997343 | 0.69 | AKR1C3 (0.42) | LMNASMN1; SMN2 | |
| SCHEMBL8740473 | 0.69 | HSD11B1 (0.35) | HSD11B1CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528694-B1 | Method for producing optically active 3-substituted-2-norbornanones and their intermediates | CHISSO CORP (JP) | 1997-04-09 | — | — | EP | disclosed |
| US-5266728-A | Method for producing optically active 3-substituted-2-norbornanones and their intermediates | CHISSO CORPORATION (JP) | 1993-11-30 | — | — | US | disclosed |
| EP-0528694-A2 | Method for producing optically active 3-substituted-2-norbornanones and their intermediates | CHISSO CORPORATION (JP) | 1993-02-24 | — | — | EP | disclosed |