Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639269 | 0.83 | HTR7 (0.65) | HTR7ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL3785373 | 0.80 | HTR7 (0.61) | HTR7ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL6777717 | 0.78 | POLB (0.59) | HTR7HSD17B10DPP4MAPTL3MBTL1 | |
| SCHEMBL4439553 | 0.77 | HTR7 (0.53) | HTR7ALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL1782448 | 0.75 | HTR7 (0.50) | HTR7ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL945670 | 0.75 | HTR7 (0.50) | HTR7ALDH1A1HSD17B10HPGDBCL2L1 | |
| Hydrochloric Acid SCHEMBL17633911 | 0.75 | HTR7 (0.61) | HTR7ALDH1A1HSD17B10BACE1DPP4 | |
| SCHEMBL7764950 | 0.75 | HTR7 (0.56) | HTR7ALDH1A1HPGDMAPK1MAPT | |
| SCHEMBL11622720 | 0.74 | HTR7 (0.59) | HTR7ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL11620914 | 0.72 | HTR7 (0.57) | HTR7ALDH1A1HSD17B10HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783486-A1 | NOVEL PROSTAGLANDIN SYNTHASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-07-16 | — | — | EP | disclosed |