Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.64 |
| ▸ | HTR2A | P28223 | 2/20 | 0.64 |
| ▸ | HTR7 | P34969 | 2/20 | 0.64 |
| ▸ | HTR6 | P50406 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780097 | 0.99 | HRH3 (0.62) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL8780099 | 0.99 | HRH3 (0.62) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL8780105 | 0.97 | TDP1 (0.63) | HRH3HTR2AHTR7HTR6TDP1 | |
| Oxalic Acid SCHEMBL8780163 | 0.92 | KDM4E (0.60) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL8780104 | 0.89 | TDP1 (0.52) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL5209621 | 0.78 | DRD1 (0.51) | CYP2D6KDM4E | |
| SCHEMBL8780092 | 0.78 | LMNA (0.54) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL8780088 | 0.78 | ATM (0.48) | HRH3HTR2AHTR7HTR6ALDH1A1 | |
| SCHEMBL8780111 | 0.78 | HRH3 (0.55) | HRH3HTR2AHTR7HTR6TDP1 | |
| Hydrochloric Acid SCHEMBL8780151 | 0.77 | HRH3 (0.97) | HRH3HTR2AHTR7HTR6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662964-B1 | HETEROCYCLIC AMINES HAVING CALMODULIN ANTAGONIST PROPERTIES | BRITISH TECH GROUP (GB) | 1997-06-11 | — | — | EP | claimed |
| EP-0662964-A1 | HETEROCYCLIC AMINES HAVING COLMODULIN ANTAGONIST PROPERTIES. | BRITISH TECH GROUP (GB) | 1995-07-19 | — | — | EP | claimed |
| WO-1994007875-A1 | HETEROCYCLIC AMINES HAVING COLMODULIN ANTAGONIST PROPERTIES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-04-14 | — | — | WO | claimed |
| EP-0662964-B1 | HETEROCYCLIC AMINES HAVING CALMODULIN ANTAGONIST PROPERTIES | BRITISH TECH GROUP (GB) | 1997-06-11 | — | — | EP | disclosed |
| US-5543422-A | HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS, FUNGICIDES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-08-06 | — | — | US | disclosed |
| EP-0662964-A1 | HETEROCYCLIC AMINES HAVING COLMODULIN ANTAGONIST PROPERTIES. | BRITISH TECH GROUP (GB) | 1995-07-19 | — | — | EP | disclosed |
| WO-1994007875-A1 | HETEROCYCLIC AMINES HAVING COLMODULIN ANTAGONIST PROPERTIES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-04-14 | — | — | WO | disclosed |