Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | PDCD4 | Q53EL6 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12446846 | 1.00 | KMT2A (0.39) | KMT2AALDH1A1GPR84MEN1FFAR1 | |
| SCHEMBL29302793 | 0.94 | KMT2A (0.39) | KMT2AALDH1A1GPR84MEN1FFAR1 | |
| SCHEMBL9457398 | 0.82 | KMT2A (0.35) | KMT2AALDH1A1GPR84MEN1FFAR1 | |
| SCHEMBL9457037 | 0.82 | KMT2A (0.35) | KMT2AALDH1A1GPR84MEN1FFAR1 | |
| SCHEMBL9457337 | 0.82 | KMT2A (0.35) | KMT2AALDH1A1GPR84MEN1FFAR1 | |
| SCHEMBL9457405 | 0.82 | KMT2A (0.35) | KMT2AALDH1A1GPR84MEN1FFAR1 | |
| SCHEMBL9457330 | 0.82 | KMT2A (0.35) | KMT2AALDH1A1GPR84MEN1FFAR1 | |
| SCHEMBL9457326 | 0.82 | KMT2A (0.35) | KMT2AALDH1A1GPR84MEN1FFAR1 | |
| SCHEMBL9457121 | 0.82 | KMT2A (0.35) | KMT2AALDH1A1GPR84MEN1FFAR1 | |
| SCHEMBL9457048 | 0.82 | KMT2A (0.35) | KMT2AALDH1A1GPR84MEN1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245056-A | PRODUCTION OF OXETANONES | HOFFMANN-LA ROCHE INC. (US) | 1993-09-14 | — | — | US | claimed |
| EP-0443449-B1 | Process for the preparation of oxetanones | HOFFMANN LA ROCHE (CH) | 1997-05-21 | — | — | EP | disclosed |
| US-5399720-A | Production of oxetanones | HOFFMANN-LA ROCHE INC. (US) | 1995-03-21 | — | — | US | disclosed |
| US-5245056-A | PRODUCTION OF OXETANONES | HOFFMANN-LA ROCHE INC. (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0443449-A2 | Process for the preparation of oxetanones | F. HOFFMANN-LA ROCHE AG (CH) | 1991-08-28 | — | — | EP | disclosed |