SCHEMBL8780210

SCHEMBL8780210

Brc1[c]c2ccsc2cc1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295852 0.73 KDM4E (0.32) CYP2A6
SCHEMBL21295873 0.67 PDPK1 (0.34)
SCHEMBL21295810 0.65 MAPT (0.34)
SCHEMBL21295811 0.64 CYP2A6 (0.47) CYP2A6
SCHEMBL21300515 0.61 KDM4E (0.41)
SCHEMBL23182 0.60
SCHEMBL452450 0.60
SCHEMBL9764660 0.60 CYP2A6 (0.32) CYP2A6
SCHEMBL70966 0.59
SCHEMBL29149 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0662964-B1 HETEROCYCLIC AMINES HAVING CALMODULIN ANTAGONIST PROPERTIES BRITISH TECH GROUP (GB) 1997-06-11 EP disclosed