Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252 | 0.75 | CYP2A6 (0.41) | CYP2A6 | |
| SCHEMBL28076506 | 0.73 | ALDH1A1 (0.39) | CYP2A6 | |
| SCHEMBL27472111 | 0.69 | ALDH1A1 (0.36) | CYP2A6 | |
| SCHEMBL13735864 | 0.68 | CYP2A6 (0.30) | CYP2A6 | |
| SCHEMBL28214534 | 0.67 | ALDH1A1 (0.35) | CYP2A6 | |
| SCHEMBL195377 | 0.67 | ALDH1A1 (0.36) | CYP2A6 | |
| SCHEMBL144203 | 0.67 | CYP2A6 (0.42) | CYP2A6 | |
| Anthracene SCHEMBL27957755 | 0.66 | RPS6KB2 (0.39) | CYP2A6 | |
| SCHEMBL1774665 | 0.66 | CYP2A6 (0.41) | CYP2A6 | |
| SCHEMBL4585002 | 0.66 | CYP2A6 (0.41) | CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049581-A | Dibenzofurans having anti-tumor activity | BURROUGHS WELLCOME CO. (US) | 1991-09-17 | — | — | US | disclosed |